The approach was consistent with what the band had done in the past, with Keenan waiting to write vocals and lyrics until instrumentals were completed. The band was quiet over the next few years, only with Tool's website announcing that guitarist Adam Jones, bassist Justin Chancellor, and drummer Danny Carey were working on instrumental material while Keenan focused his efforts on Puscifer. However, by early 2008, at the 50th Grammy Awards, Keenan announced to MTV that the band would begin writing new material for their fifth studio album 'right away'. After this, frontman Maynard James Keenan mentioned that he saw Tool breaking up in the near future, and focused on his side project, Puscifer.

The band toured heavily in support of the album, playing more than 200 shows through 2007. It topped the US Billboard 200 album chart and was certified platinum by the RIAA, indicating more than one million units sold, a month later. In 2006, Tool released their fourth studio album, 10,000 Days. The title track also holds the Guinness World Record for longest song ever to chart on the Billboard Hot 100. Two songs off the album received Grammy nominations, the first single ' Fear Inoculum', for the Grammy Award for Best Rock Song, and ' 7empest', for the Grammy Award for Best Metal Performance, with the latter winning the award. The album topped five other national album charts in its opening week as well.

The album topped the US Billboard 200 chart, their third in a row to do so, selling over 270,000 album-equivalent units. It was released to critical acclaim, with reviewers generally agreeing that the band had successfully refined their established sound. It is the band's first album in 13 years, due to creative, personal, and legal issues band members encountered since the release of 10,000 Days. It was released on August 30, 2019, through Tool Dissectional, Volcano Entertainment, and RCA Records. Fear Inoculum is the fifth studio album by American rock band Tool.

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